There are three different keyboard shortcuts to take a screenshot in MacOS:
- Cmd + Shift + 3: Take a screenshot of the entire screen
- Cmd + Shift + 4: You select an area for a screenshot
- Cmd + Shift + 5: Capture screenshots and videos
By default, all screenshots are saved on your desktop. To change that, go to the extended screenshot menu with Cmd + Shift + 5.
Under Options > Other Location... you can select a new place for your screenshots. For example, I created a folder named "Screenshots Macbook" in my iCloud Drive. As a result, my desktop is not constantly full and at the same time I have the screenshots in my iCloud with me wherever I go.